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 Scientific study published in the International Journal of Impotence Research
(volume 13, sup. 4, Oct-2001) and presented at the 4th annual European Society for Sexual
and Impotence Research (ESSIR) Conference (Rome, Oct. 2001).
Scroppo FI., Mancini M., Maggi M.*,
ColpiGM. Andrology Service, Ospedale SanPaolo-Polo Universitario, Milano (Italy).
* Andrology Unit, Dip. Fisiopat. Clin., Università di Firenze, Firenze (Italy).
Introduction
And Objectives
Peyronie's fibrotic lesions frequently affect the dorsal tunica albuginea and the septum of the
penis. Subsequently they can lead to plaque development, penile deformity and pain during
erection.
Duplex sonographic scanning may allow an objective evaluation of the fibrosis,
assessing the thickening of the tunica albuginea and penile plaques. The aim of this study is to
investigate the efficacy of mechanical penile stretching (PS) to reduce plaque thickness and
penile deformity during erection.
Materials
And Methods
Eight patients (age 58.5±5.3 yrs.) affected by Peyronie's disease, apparently unmodified at
least for the latest 3 months and causing penile curvature during erection (PEC), were trained
to use a mechanical penis stretcher. None of them complained about erectile dysfunction
according to IIEF test, and penile pain.
After intracavernous injection ofPgE1 5-15mgto obtain full erection (assessed by both Digital
Inflection Rigidometry and palpation), cross scanning of tunica albuginea by duplex
sonography, photographs of the erect penis according to Kelami's projections, and penile
diameters and length measurements were performed before and after daily home PS application (at least four hours / day)
for 3 to 6 months.
Individual follow-up examinations were scheduled after 3 and 6 months. At the present time,
all patients have concluded the 3-month follow-up, and two of them the 6-month one.
Results
The tunica highest thickness resulted 1.8±0.6mmbefore and 1.6±0.3mmafterPS(n.s.).
The septum latero-lateral maximum thickness was 2.2±0.7mmbefore and 1.8±0.8mmafter
PS (n.s.).
Penile length, dorsally measured from penopubic angle to
meatus, was 100.5±27.3
mmbefore and 104.6±22.2mmafter PS (n.s.). Photographs showed that PEC decreased from
34.1±4.9° before to 20.0±12.2° after PS (p<0.05). The treatment was well tolerated (no severe
complication and no drop out occurred).
Result Charts
Conclusion
These results suggest a promising use of PS in selected Peyronie's patients affected by penile curvature without erectile dysfunction.
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